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XCOLLITE

INGREDIENT:

Skimmed milk, mannitol, dextrose, blackcurrant powder, collagen, vitamin c (ascorbic acid), colostrum, l-Cysteine, yeast extract, astaxanthin, acesulfame-K, lactoferrin, apple stem cell.

PACKAGING SIZE:

      1000 mg x 60 tablets

SERVING SUGGESTION:

      Chew 2 tablets per day during empty stomach

BENEFITS OF INGREDIENTS:

HYDROLYZED MARINE COLLAGEN

Collagen is a kind of spiralled protein that is made of 3 peptides. It plays the important roles of supporting organs and protecting the body when present in skin, muscle, bone, teeth, eyes, etc.

Collagen is a kind of spiralled protein that is made of 3 peptides. It plays the important roles of supporting organs and protecting the body when present in skin, muscle, bone, teeth, eyes, etc.At some point, usually in late twenties, your body will no longer be producing the full amount of collagen it requires to repair your body, and a slow decline occurs. From the Age of 25 it is thought your body loses collagen at 1.5 % every year (e.g. age 35 loss = 15%, age 45 loss = 30% etc.) therefore this system is designed to stimulate collagen production and help replace that loss.

Collagen has been found to strengthen brittle nails. The effect of daily collagen ingestion on the human scalp has been studied, this showed dramatic increases in the diameter of the hair ranging between 9.3% - 11.3%. The strength of the hair was also tested and this was found to have also increased.

VITAMIN C

Vitamin C plays multiple roles in maintaining healthy skin. It is a known potent antioxidant that can be usedtopically and orally to treat and prevent skin changes associated with ageing (Telang, 2013). Unlike most other animals, humans do not synthesise vitamin C and therefore the consumption of optimal amounts of vitamin C is essential. However, research shows that the recommended daily allowance (RDA) of vitamin C is lower than the body needs and subsequently it appears difficult to reach an effective dose of vitamin C through food consumption alone.

To achieve optimal health, researchers suggest that daily vitamin C supplementation of 1 g per day is required (Deruelle and Baron, 2008). Vitamin C is also a potent anti-inflammatory nutrient. It inhibits nf-kB, which is responsible for the activation of a number of pro-inflammatory cytokines. Therefore, vitamin C can be used to treat conditions like acne vulgaris and rosacea, while promoting wound healing and preventing post-inflammatory hyperpigmentation.

In addition to stimulating qualitative changes in the collagen molecule, it has been proposed that vitamin C influences quantitative collagen synthesis. Vitamin C serves as a cofactor for prolysyl and lysyl hydroxylase—the enzymes responsible for stabilising and cross-linking the collagen molecules. Another mechanism by which vitamin C influences the collagen synthesis is via stimulation of lipid peroxidation, where the product of this process (MDA) encourages collagen gene expression.

COLOSTRUM

Colostrum is breast milk produced after the birth of the new born and lasts for 2-4 days. Colostrum is very important part of breast milk and lays down the immune system and confers growth factors and other protective factors for the young ones in mammals. This is the source of passive immunity transferred to the baby from the mother. There are two primary components of colostrum, immune factors and growth factors. Colostrum also contains vitamins, minerals and amino acids.

Bovine colostrum (BC) has been studied for important therapeutic effect in various chronic infections like bacterial, viral, parasitic or fungal. When given as a nutritional supplement in certain chronic conditions like chronic fatigue syndrome, infectious diarrhea, sinusitis and fibromyalgia, it leads to immunogical boosting. The biological value of bovine colostrum in present day medical practice is documented in clinical trials and large databases containing case reports and anecdotal findings.

The main actions include an antibacterial effect and modulation of immune response with the ability to neutralize lipopolysaccharides arising from gram negative bacterial pathogens. It has been found to be effective in infantile hemorrhagicdiarrheas, other diarrheasabd reduces the likelihood of disease progressing to haemolytic uremic syndrome. It has also been tested in H pylori infection and diarrhea in immunodeficiency.

L-CYSTEINE

L-cysteine is a proteinogenic amino acid contributing to building protein and includes the element sulphur.It can be synthesised in the human liver and is therefore not an essential amino acid.It should be however, be supplemented in order to cover the required daily amounts.

L-cysteine is promoted for skin whitening, which is claimed to be 3-5 times more potent than Glutathione. Natural sources of L-cysteine include poultry, yogurt, egg yolks, red peppers, garlic, onions, broccoli, Brussel sprouts, oats and wheat germ.

L-cysteine along with L-glutamic acid and glycine is the rate-limiting precursor in the synthesis of GSH peroxidase and has been found that high concentrations of L-cysteine reduced the tyrosinase activity and produced more pheomelanin. Hence L-cysteine peptide is promoted as skin whitening agent. Besides, L-cysteine could boost immune system, increase mail fertility, reduces inflammation and combats osteoporosis.


YEAST EXTRACT CEREPRON-F

Cerepron is Yeast Extract with High Thioredoxin Activity (TRX) which is protein with 11,000 molecular weight that has antioxidant and anti-inflammatory effects. TRX exists in the body system of all organisms to protect organisms from UV, radiation, viruses, and bacterial infections.

Cerepron will suppresses melanin synthesis and increase gluthation. Study shows that the amount of melanin decreased in concentration-dependent manner of cerepron. Furthermore, it will increase total glutathione amount in the blood which support beautiful white skins.



ASTAXANTHIN

Astaxanthin is a carotenoid with antioxidant properties similar to beta-carotene. It provides the red coloring of salmon, trout, shrimp and crab as well as some forms of algae, including Haematococcuspluvialis.

Astaxanthin has six biological profiles: pro-vitamin A, anti-inflammatory activity, biological response modifier, blood brain barrier pass, blood retina barrier pass and antioxidant.

As an antioxidant, Astaxanthin aids in treating conditions such as hypertension, diabetes, hypercholesterolemia, arteriosclerosis, some forms of cancer and some skin disorders. Astaxanthin acts as an antioxidant by scavenging free radicals, quenching singlet oxygen, quenching triplet oxygen and halting chain reactions, and has the highest antioxidant activities when compared to other carotenoids. One in vivo study conducted in 1997 by the Nutrition/Foods Society determined that Astaxanthin inhibits LDL oxidation most effectively with a 3.6 mg/day dose, with subjects experiencing positive effects within 60 minutes of consumption. Astaxanthin also has chemo-preventive effects on several types of cancer.

Astaxanthin can be found as esters (derivatives of Astaxanthin) and isomers (3-dimensional arrangements of Astaxanthin). Humans can biosynthesize Astaxanthin from sources including micro-algae, yeast (Phaffiarhodozyma), bacteria (Agrobacterium aurantiacum) and higher plants (Adonis aestivalis). Astaxanthin is also obtainable from food sources including crustaceans such as Antarctic krill and fish such as Coho salmon. ,H. PluvialisAstaxanthin is more stable because it is esterified, and it is a source of linolenic fatty acids and other nutrients. In addition, this type of Astaxanthin is more readily absorbed, can be mass produced in a cost efficient way and is a safe, natural source.

Skin pigmentation such as stains and freckles are caused by excessive uneven production of melanin. It is known by reducing tyrosinase activity will reduce pigmentation. This can be achieved by inhibiting the synthesis of tyrosinase or by using an antagonist substrate for tyrosinase. Pigmentation is also prevented by inhibiting auto-oxidation of dopa and suppressing inflammatory reactions such as erythema following UV irradiation. Whitening agents such as Arbutin, Kojic Acid and Ascorbic acid derivative inhibit tyrosinase synthesis. The study was conducted the potential whitening effect of Astaxanthin relative to the other whitening agents.

LACTOFERRIN

Lactoferrin is a naturally occurring iron-binding protein found in milk that has been shown to have important and diverse biological functions. The abundance of lactoferrin in human milk is an indication of its role in infant nutrition, with human infants ingesting up to 3g of lactoferrin per day from breast milk during the first week of life (Reiter, 1985).

Lactoferrin may be an important component of the immune system because of its potent antimicrobial activity that provides protection against a multitude of infectious agents. Lactoferrin has also been shown to have anti-inflammatory and antioxidant activities as well as enhancing iron status in vulnerable groups such as infants (Lonnerdal, 2009).

Its multiple activities lie in its capacity to bind iron and to interact with the molecular and cellular components of hosts and pathogens. Lf can bind and sequester lipopolysaccharides, thus preventing pro-inflmmatory pathway activation, sepsis and tissue damages.

APPLE STEM CELL

Studies show that apple stem cells boosts production of human stem cells, protect the cell from stress, and decreases wrinkles. The internal fluid of these plant cells contains components that help to protect and maintain human stem cells. Apple stem cells contain metabolites to ensure longevity as the tree is known for the fact that its fruit keep well over long periods of time.

When tested in vitro, the apple stem cell extract was applied to human stem cells from umbilical cords and was found to increase the number of the stem cells in culture. Furthermore, the addition of the ingredient to umbilical cord stem cells appeared to protect the cells from environmental stress such as UV light. Apple stem cells do not have to be fed through the umbilical cord to benefit our skin! The extract derived from the plant cell culture technology is being harnessed as an active ingredient in anti-aging skincare products.